There's just one thing I want to say. People that are saying others need to take a break, or take a chill pill, or what have you; really need to stop. Just because they don't have as thick of a skin as you, doesn't mean they should have to tolerate somebody poking them in a game. It definitely doesn't mean that they are immature people that have to grow up, or even that they are angry people. It just means that something is annoying them, nothing more or less.
If somebody is annoyed at something, telling them to "calm down," "relax," "take a chill pill," is just going to antagonize them further. Taking away what is annoying them is what pacifies them.